● `color{violet}("Urine formation")` involves three main processes namely, `color{brown}("glomerular filtration, reabsorption and secretion")`, that takes place in different parts of the `color{violet}("nephron.")`
● The first step in `color{violet}("urine formation")` is the `color{violet}("filtration of blood")`, which is carried out by the `color{violet}("glomerulus")` and is called `color{brown}("glomerular filtration.")`
● On an average, `color{brown}("1100-1200 ml of blood")` is filtered by the `color{violet}("kidneys")` per minute which constitute roughly 1/5th of the `color{violet}("blood pumped")` out by each ventricle of the `color{violet}("heart")` in a minute.
● The `color{violet}("glomerular capillary blood pressure")` causes filtration of blood through 3 layers, i.e., the `color{brown}("endothelium")` of `color{violet}("glomerular blood vessels,")` the `color{brown}("epithelium")` of `color{violet}("Bowman’s capsule ")` and a `color{brown}("basement membrane")` between these two layers.
● The `color{violet}("epithelial cells of Bowman’s capsule")` called `color{brown}("podocytes")` are arranged in an intricate manner so as to leave some minute spaces called `color{brown}("filtration slits or slit pores.")`
● `color{violet}("Blood is filtered")` so finely through these membranes, that almost all the constituents of the `color{violet}("plasma")` except the proteins pass onto the `color{violet}("lumen")` of the `color{violet}("Bowman’s capsule.")`
● Therefore, it is considered as a process of `color{brown}("ultra filtration.")`
● The amount of the filtrate formed by the `color{violet}("kidneys")` per minute is called `color{brown}("glomerular filtration rate (GFR)")`. GFR in a healthy individual is approximately `color{brown}("125 ml/minute,")` i.e., 180 litres per day !
● `color{violet}("Urine formation")` involves three main processes namely, `color{brown}("glomerular filtration, reabsorption and secretion")`, that takes place in different parts of the `color{violet}("nephron.")`
● The first step in `color{violet}("urine formation")` is the `color{violet}("filtration of blood")`, which is carried out by the `color{violet}("glomerulus")` and is called `color{brown}("glomerular filtration.")`
● On an average, `color{brown}("1100-1200 ml of blood")` is filtered by the `color{violet}("kidneys")` per minute which constitute roughly 1/5th of the `color{violet}("blood pumped")` out by each ventricle of the `color{violet}("heart")` in a minute.
● The `color{violet}("glomerular capillary blood pressure")` causes filtration of blood through 3 layers, i.e., the `color{brown}("endothelium")` of `color{violet}("glomerular blood vessels,")` the `color{brown}("epithelium")` of `color{violet}("Bowman’s capsule ")` and a `color{brown}("basement membrane")` between these two layers.
● The `color{violet}("epithelial cells of Bowman’s capsule")` called `color{brown}("podocytes")` are arranged in an intricate manner so as to leave some minute spaces called `color{brown}("filtration slits or slit pores.")`
● `color{violet}("Blood is filtered")` so finely through these membranes, that almost all the constituents of the `color{violet}("plasma")` except the proteins pass onto the `color{violet}("lumen")` of the `color{violet}("Bowman’s capsule.")`
● Therefore, it is considered as a process of `color{brown}("ultra filtration.")`
● The amount of the filtrate formed by the `color{violet}("kidneys")` per minute is called `color{brown}("glomerular filtration rate (GFR)")`. GFR in a healthy individual is approximately `color{brown}("125 ml/minute,")` i.e., 180 litres per day !